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Search Results for " Monopolar spindle 1 "

ターゲット

13

阻害剤

1733

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T3434 BAY1217389 Kinesin
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
T16130 Mps1-IN-3 Kinesin
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
T2689 AZ3146 AZ 3146 Kinesin
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
T14765 BOS-172722 Kinesin
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
T2313 MPI-0479605 Apoptosis , Kinesin
MPI-0479605 is an ATP competitive and selective inhibitor.
T12237 NMS-P715 Casein Kinase , Kinesin , MELK , MAPK
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T1839 Mps1-IN-2 Kinesin , PLK
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
T8487 Empesertib BAY 1161909 Kinesin
Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
T14906 CCT251455 Kinesin
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T73483 RMS-07
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the...
T17007 TC-Mps1-12 Kinesin
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
T73229 Mps1-IN-4
Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.
T37050 MPS1/TTK Inhibitor MPS1/TTK Inhibitor
MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. It inhibits MPS1 phosphory...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-01023 CD38 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05239 HER2/ERBB2 Protein, Human, Recombinant , Biotinylated Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02031 B7-H3 Protein, Human, Recombinant (His) Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc) Human HEK293
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01226 CD4 Protein, Mouse, Recombinant (His) Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His) Human HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01938 CD98 Protein, Human, Recombinant (His) Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01283 Glypican 3/GPC3 Protein, Human, Recombinant (His) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-01851 CD73 Protein, Human, Recombinant (His) Human HEK293
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099 CD63 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01608 Decorin Protein, Human, Recombinant (His) Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His) Human HEK293
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-01305 OSMR Protein, Human, Recombinant (His) Human HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-03958 TGF alpha Protein, Human, Recombinant Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-01853 SIRP gamma Protein, Human, Recombinant (His) Human HEK293
Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunog...
TMPY-04698 HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05208 PD-L1 Protein, Human, Recombinant Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05016 HHLA2 Protein, Human, Recombinant (His) Human HEK293
B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPK-01393 Tenascin Protein, Mouse, Recombinant (His) Mouse HEK293
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
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AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
CD38 Protein, Human, Recombinant (His)
TMPY-01023
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant , Biotinylated
TMPY-05239
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
TMPY-00399
Species: Human
Expression System: HEK293
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
CD155/PVR Protein, Human, Recombinant (hFc)
TMPY-00699
Species: Human
Expression System: HEK293
CD4 Protein, Mouse, Recombinant (His)
TMPY-01226
Species: Mouse
Expression System: HEK293
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
TMPY-01050
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293
CD98 Protein, Human, Recombinant (His)
TMPY-01938
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His)
TMPY-01283
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293
CD73 Protein, Human, Recombinant (His)
TMPY-01851
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
CD63 Protein, Human, Recombinant (His)
TMPY-02099
Species: Human
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
TMPY-01608
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293
LILRB5/CD85c Protein, Human, Recombinant (His)
TMPY-04826
Species: Human
Expression System: HEK293
OSMR Protein, Human, Recombinant (His)
TMPY-01305
Species: Human
Expression System: HEK293
TGF alpha Protein, Human, Recombinant
TMPY-03958
Species: Human
Expression System: E. coli
SIRP gamma Protein, Human, Recombinant (His)
TMPY-01853
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)
TMPY-04698
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant (His), Biotinylated
TMPY-04949
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant
TMPY-05208
Species: Human
Expression System: HEK293
HHLA2 Protein, Human, Recombinant (His)
TMPY-05016
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
TMPY-04413
Species: Human
Expression System: Baculovirus-Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977)
TMPY-04753
Species: Human
Expression System: Baculovirus-Insect Cells
Tenascin Protein, Mouse, Recombinant (His)
TMPK-01393
Species: Mouse
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293